Creatine kinase-MB (CK-MB) is a form of an enzyme that is found primarily in the heart muscles. This test measures the CK-MB in the blood. The CK-MB is one of three forms (isoenzymes) of the enzyme in creatine kinase (CK). These isoenzymes include CK-MM (found in skeletal muscles and the heart), CK-MB (found mostly in the heart, but small amounts are found in skeletal muscles), and CK-BB (mostly found in the brain and smooth muscles, such as the intestines and uterus).
It is recommended:To diagnose a heart attack.To diagnose subsequent heart attacks.To monitor heart damage.This test is likely to be ordered if a person has chest pain or if a person’s diagnosis is unclear, such as if a person has non-specific symptoms like shortness of breath, fatigue, nausea, or dizziness.
The Creatine Phosphokinase (CPK)-MB test measures:The creatine kinase MB (CK-MB) test analyses the amount of CK-MB enzyme. They are mostly found in the heart muscles, and elevated levels of CK-MB are an indication of heart damage or heart attack. It also monitors the efficiency of ongoing heart treatment.This CK-BB rarely gets into the blood, and CK-MB will typically only be present in significant amounts when the heart is damaged. A CK test analyses the total level but does not distinguish between the three isoenzymes. When there is an increase in the amount of CK present in the blood, the CK-MB test can be used to determine whether it is due to heart damage or might be related to skeletal muscle injury.
The Creatine Phosphokinase (CPK)-MB test is prescribed by your doctor after completing the assessment of your conditions.
5–25 IU/L
We require a blood sample for this test.
This test can be taken at any time during the day.
Fasting is not required for this test.
There are no specific precautions for this test.
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